2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol(CAS: 728-40-5)

2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol (CAS: 728-40-5) is a crystalline solid with a molecular weight of approximately 274.18 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is known for its reactivity, particularly towards reduction and nitro group substitution reactions. It forms a deep red crystalline solid, and its melting point is around 75-77°C.

2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol is typically synthesized through the nitration of 2,6-bis(2-methylpropyl)phenol. This involves treating the phenol with a mixture of nitric acid and sulfuric acid under controlled conditions. The reaction is carried out in a fume hood due to the generation of toxic gases. The yield is around 70-80%, and mild conditions are used to improve selectivity and reduce by-products.

2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol (CAS: 728-40-5) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those that require nitro functionalities. It is also utilized in the polymer industry for the production of specialty plastics and elastomers. Due to its reactivity, it finds applications in the development of sensors and electronic materials, including organic semiconductors and photodiodes.

Handling 2,6-Bis(2-methyl-2-propanyl)-4-nitrophenol (CAS: 728-40-5) requires strict safety measures. It is recommended to wear proper personal protective equipment (PPE), including gloves and safety glasses. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation of toxic fumes. In case of a spill, it should be cleaned up immediately using absorbent materials, and the area should be thoroughly washed down. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.