Compound Q&A
How is 4-(4H-1,2,4-triazol-4-yl)benzoic acid (CAS: 157069-48-2) typically synthesized?
Answer
4-(4H-1,2,4-triazol-4-yl)benzoic acid is usually synthesized via the condensation of 4-amino-benzoic acid with 1,2,4-triazole. The reaction is typically performed in an aqueous medium at room temperature with a yield of around 70-80%. This process does not require specific catalysts but can be optimized for better selectivity and yield with temperature and solvent adjustments.
About
CAS No
157069-48-2
English Name
4-(4H-1,2,4-triazol-4-yl)benzoic acid
Molecular Formula
C9H7N3O2
Molecular Weight
189.17 g/mol
SMILES
C1=CC(=CC=C1C(=O)O)N2C=NN=C2
InChIKey
QCNDLFQKKMPZKH-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:29
