Compound Q&A
How is Methyl 2,6-difluoro-3-nitrobenzoate (CAS: 84832-01-9) typically synthesized?
Answer
Methyl 2,6-difluoro-3-nitrobenzoate can be synthesized through the nitration of 2,6-difluorobenzoic acid followed by esterification with methanol. Commonly, this process involves the use of nitric acid and sulfuric acid as the nitrating mixture, with precise temperature control to ensure the desired product is formed with high selectivity and yield. Post-synthesis, the product is typically purified by recrystallization.
About
CAS No
84832-01-9
English Name
Methyl 2,6-difluoro-3-nitrobenzoate
Molecular Formula
C8H5F2NO4
Molecular Weight
217.13 g/mol
SMILES
COC(=O)c1c(F)ccc([N+](=O)[O-])c1F
InChIKey
CIHHBTMZOLRCRL-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
