Compound Q&A
How is 4-(Benzyloxy)-2(1H)-pyridinone (CAS: 53937-02-3) typically synthesized?
Answer
4-(Benzyloxy)-2(1H)-pyridinone is commonly synthesized through the condensation of benzylamine and 2-hydroxypyridine. The reaction proceeds efficiently with a yield of about 80%. The process typically involves heating the mixture under reflux conditions in the presence of an appropriate catalyst. Commonly used catalysts include phosphorus oxychloride or chlorotriethylsilane. The product can be purified by recrystallization from suitable solvents.
About
CAS No
53937-02-3
English Name
4-(Benzyloxy)-2(1H)-pyridinone
Molecular Formula
C12H11NO2
Molecular Weight
201.23 g/mol
SMILES
C1=CC=C(C=C1)COC2=CC(=O)NC=C2
InChIKey
DOVNUEPFPBWTSV-UHFFFAOYSA-N
Last Updated: 2025-10-13 19:39
