How is (1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-azetidinyl)acetic acid (CAS: 183062-96-6) typically synthesized?

(1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-azetidinyl)acetic acid is typically synthesized via a multi-step process involving the protection of the azetidinone functionality followed by acetylation and subsequent deprotection. Commonly, this involves using reagents such as tert-butyldimethylsilyl chloride for protection, followed by acetic anhydride for acetylation, and finally, HBr for deprotection. The overall yield is around 70-80%, with good regioselectivity.