Compound Q&A

How is 3-(Benzyloxy)aniline (CAS: 1484-26-0) typically synthesized?

Answer

3-(Benzyloxy)aniline
3-(Benzyloxy)aniline is typically synthesized via the Feigl reaction, where an anilide is reduced and then alkylated with benzyl chloride. The reaction involves the use of hydrogenation catalysts like palladium on carbon and requires the addition of an acid scavenger. This method provides good yields and high selectivity for the desired product.

About

CAS No 1484-26-0
English Name 3-(Benzyloxy)aniline
Molecular Formula C13H13NO
Molecular Weight 199.25 g/mol
SMILES C1=CC=C(C=C1)COC2=CC=CC(=C2)N
InChIKey IGPFOKFDBICQMC-UHFFFAOYSA-N
Last Updated: 2025-10-13 11:18

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