Compound Q&A
How is [3,5-Bis(trifluoromethyl)phenyl]acetic acid (CAS: 85068-33-3) typically synthesized?
Answer
![[3,5-Bis(trifluoromethyl)phenyl]acetic acid](https://static.chemtradehub.com/structs/850/85068-33-3-3123.webp "[3,5-Bis(trifluoromethyl)phenyl]acetic acid")
[3,5-Bis(trifluoromethyl)phenyl]acetic acid (CAS: 85068-33-3) can be synthesized by the acetylation of 3,5-bis(trifluoromethyl)phenol using acetic anhydride in the presence of a catalyst like pyridine. The reaction is typically carried out under mild conditions to achieve high yield and selectivity. This compound is also synthesized by the oxidation of 3,5-bis(trifluoromethyl)toluene with sodium hypochlorite.
About
CAS No
85068-33-3
English Name
[3,5-Bis(trifluoromethyl)phenyl]acetic acid
Molecular Formula
C10H6F6O2
Molecular Weight
272.14 g/mol
SMILES
OC(=O)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F
InChIKey
PAWSKKHEEYTXSA-UHFFFAOYSA-N
Last Updated: 2025-09-25 13:48
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