Compound Q&A
How is Cidofovir Dihydrate (CAS: 149394-66-1) typically synthesized?
Answer
Cidofovir dihydrate is typically synthesized through a multistep process involving the condensation of 2'-deoxyguanosine with 2-hydroxy-5-nitroimidazole-1-ylidene, followed by reduction and hydration. The synthesis involves the use of reagents such as sodium hydride and acetic anhydride. The yield is moderate, around 50-60%, and the reaction conditions are optimized for selectivity and purity.
About
CAS No
149394-66-1
English Name
Cidofovir Dihydrate
Molecular Formula
C8H18N3O8P
Molecular Weight
315.22 g/mol
EINECS
814-987-8
SMILES
C1=CN(C(=O)N=C1N)CC(CO)OCP(=O)(O)O.O.O
InChIKey
FPKARFMSZDBYQF-ILKKLZGPSA-N
Last Updated: 2025-09-25 13:48
