Compound Q&A
How is Rupatadine (CAS: 158876-82-5) typically synthesized?
Answer
Rupatadine is synthesized via a multi-step process, starting with the synthesis of the key intermediate, 3-(4-chlorophenyl)-N-(2,6-dichlorophenyl)propan-1-amine, followed by coupling with a suitable alcohol under catalysis by a palladium-based catalyst, achieving a yield of about 75%.
About
CAS No
158876-82-5
English Name
Rupatadine
Molecular Formula
C26H26ClN3
Molecular Weight
415.96800000000025 g/mol
SMILES
CC1=CC(=CN=C1)CN2CCC(=C3C4=C(CCC5=C3N=CC=C5)C=C(C=C4)Cl)CC2
InChIKey
WUZYKBABMWJHDL-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21
