Compound Q&A
How is 1-(2-Methyl-5-nitrophenyl)guanidine nitrate (CAS: 152460-08-7) typically synthesized?
Answer
1-(2-Methyl-5-nitrophenyl)guanidine nitrate (1:1) is typically synthesized by the nitration of 2-methyl-5-nitroaniline with nitric acid in the presence of a strong acid catalyst. The reaction yields a 1:1 nitrate complex with high selectivity and a yield of around 85%. The process requires careful temperature control to prevent side reactions and decomposition.
About
CAS No
152460-08-7
English Name
1-(2-Methyl-5-nitrophenyl)guanidine nitrate (1:1)
Molecular Formula
C8H11N5O5
Molecular Weight
257.2 g/mol
SMILES
CC1=C(C=C(C=C1)[N+](=O)[O-])N=C(N)N.[N+](=O)(O)[O-]
InChIKey
IINMQQJNRFDBMV-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18
