Compound Q&A

How is 5-Isoquinolinesulfonyl chloride hydrochloride (CAS: 105627-79-0) typically synthesized?

Answer

5-Isoquinolinesulfonyl chloride hydrochloride (1:1)
5-Isoquinolinesulfonyl chloride hydrochloride is typically synthesized by reacting isoquinoline with sulfonyl chloride in the presence of a suitable base such as pyridine. The reaction is often performed under anhydrous conditions to avoid hydrolysis, and the yield can be enhanced by using appropriate catalysts and optimizing reaction conditions.

About

English Name 5-Isoquinolinesulfonyl chloride hydrochloride (1:1)
Molecular Formula C9H7Cl2NO2S
Molecular Weight 264.13 g/mol
SMILES C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)Cl.Cl
InChIKey GZQNTWHQJJVIAK-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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