Compound Q&A

How is 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid (CAS: 21256-18-8) typically synthesized?

Answer

3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid can be synthesized by reacting 4,5-diphenyl-1,3-oxazole-2-carboxylic acid chloride with 1-propanol. The reaction typically requires the use of a suitable base like pyridine to enhance the reaction rate. The product is purified by recrystallization from ethanol, yielding a white solid with a high yield and excellent purity.

About

CAS No 21256-18-8
English Name 3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
Molecular Formula C18H15NO3
Molecular Weight 293.32 g/mol
SMILES C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3
InChIKey OFPXSFXSNFPTHF-UHFFFAOYSA-N
Last Updated: 2025-09-05 16:09

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