(S)-(-)-N-(5-NITRO-2-PYRIDYL)PROLINOL(CAS: 88374-37-2)

(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol is a white crystalline solid with a molecular weight of approximately 228.16 g/mol. It has a low solubility in water but good solubility in organic solvents such as methanol and ethanol. The compound is known for its reactivity, particularly towards nucleophilic substitution reactions and condensation reactions. It can form stable complexes and is used in various synthetic chemistry applications.

(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol can be synthesized through the condensation reaction of 5-nitropyridine and proline. The reaction is typically catalyzed by an appropriate base such as potassium carbonate or sodium hydride. The process involves the formation of an intermediate that is subsequently protonated to form the desired prolinol derivative. This method provides good yield and selectivity.

(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol is primarily used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in polymer chemistry, where it can be used as a monomer or cross-linking agent. Additionally, it has potential uses in sensor technology and semiconductor manufacturing due to its unique chemical properties.

When handling (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a laboratory coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.