(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol

Basic Information

View in Editor

CAS Number

88374-37-2

Molecular Formula

C10H13N3O3

Molecular Weight

223.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

81.0 to 84.0 deg-C

Refractive Index

-163.5 ° (C=1, EtOH)

SMILES

View in Editor

C1CC(N(C1)C2=NC=C(C=C2)[N+](=O)[O-])CO

InChI

InChI=1S/C10H13N3O3/c14-7-9-2-1-5-12(9)10-4-3-8(6-11-10)13(15)16/h3-4,6,9,14H,1-2,5,7H2/t9-/m0/s1

InChIKey

YBARIBJRNJYVTK-VIFPVBQESA-N

LogP

1.53910

Complexity

256

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-Pyrrolidinemethanol,1-(5-nitro-2-pyridinyl)-, (2S)-
(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol
[(2S)-1-(5-nitropyridin-2-yl)pyrrolidin-2-yl]methanol
(S)-(-)-1-(5-Nitro-2-pyridyl)-2-pyrrolidinemethanol
2-(N-Prolinol)-5-nitropyridine
(S)-(1-(5-Nitropyridin-2-yl)pyrrolidin-2-yl)methanol
2-Pyrrolidinemethanol, 1-(5-nitro-2-pyridinyl)-, (2S)-
N0540
(S)-(-)-(5-NITRO-2-PYRIDYL)PROLINOL
(2S)-1-(5-Nitro-2-pyridyl)-2-pyrrolidinemethanol
(2s)-1-(5-nitro-2-pyridinyl)-2-pyrrolidinemethanol
(S)-(-)-1-(5-Nitro-2-
DTXSID00659936
CS-0315482
(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol, >/=99%
FS-5901
SCHEMBL5822677
AKOS015833295
T73035
[(2S)-1-(5-Nitropyridin-2-yl)pyrrolidin-2-yl]methanol
MFCD00145250
88374-37-2

MDL Number

MFCD00145250

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol (CAS: 88374-37-2)?

(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol is a white crystalline solid with a molecular weight of approximately 228.16 g/mol. It has a low solubility in water but good solubility in organic solvents such as methanol and ethanol. The compound is known for its reactivity, particularly towards nucleophilic substitution reactions and condensation reactions. It can form stable complexes and is used in various synthetic chemistry applications.

How is (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol (CAS: 88374-37-2) typically synthesized?

(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol can be synthesized through the condensation reaction of 5-nitropyridine and proline. The reaction is typically catalyzed by an appropriate base such as potassium carbonate or sodium hydride. The process involves the formation of an intermediate that is subsequently protonated to form the desired prolinol derivative. This method provides good yield and selectivity.

What industries use (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol (CAS: 88374-37-2)?

(S)-(-)-N-(5-Nitro-2-pyridyl)prolinol is primarily used in the pharmaceutical industry for the synthesis of certain drugs and intermediates. It also finds applications in polymer chemistry, where it can be used as a monomer or cross-linking agent. Additionally, it has potential uses in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol (CAS: 88374-37-2)?

When handling (S)-(-)-N-(5-Nitro-2-pyridyl)prolinol, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a laboratory coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal guidelines.