Trimetazidine(CAS: 5011-34-7)

Trimetazidine is a white to off-white crystalline powder with a molecular weight of approximately 256.31 g/mol. It is sparingly soluble in water and ethanol. Trimetazidine is relatively stable under normal storage conditions but can react with bases. It is not flammable and has a relatively low reactivity profile.

Trimetazidine is typically synthesized through a multistep process involving the condensation of 2,4-dinitroaniline and 2,4-dinitrophenol. The reaction is catalyzed by a Lewis acid and proceeds through a series of intermediates, ultimately yielding Trimetazidine with good yield and selectivity. This method ensures high purity and efficiency in production.

Trimetazidine (CAS: 5011-34-7) is primarily used in the pharmaceutical industry for treating cardiovascular diseases, such as angina pectoris. It is also used in medical research and can be found in some sensor applications, though its main application is in the pharmaceutical sector.

When handling Trimetazidine (CAS: 5011-34-7), it is important to wear personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up promptly using appropriate absorbent materials and discarded according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and storage information.