Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (1:1)(CAS: 176977-85-8)

Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS: 176977-85-8) is a crystalline solid with a molecular weight of approximately 239.6 g/mol. It has a solubility of 0.2 g/L in water and is slightly soluble in ethanol. The compound is moderately reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a dry place to avoid hydrolysis.

Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS: 176977-85-8) is typically synthesized by reacting methyl 4-chloro-2-pyridinecarboxylate with hydrochloric acid. The reaction is conducted in a solvent such as dichloromethane or ethyl acetate, and the yield is usually around 85%. The use of a phase transfer catalyst can improve selectivity and yield.

Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS: 176977-85-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the modification of polymers, and in the sensor industry for the development of gas sensors. Additionally, it has potential uses in semiconductor manufacturing for etching processes.

When handling Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS: 176977-85-8), it is important to use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area, preferably in a fume hood. Spills should be cleaned up using an appropriate absorbent material and the area should be flushed with water. Safety data sheets (SDS) should always be consulted for detailed safety information.