1-[4-(Benzyloxy)-3-nitrophenyl]ethanone(CAS: 14347-05-8)

1-[4-(Benzyloxy)-3-nitrophenyl]ethanone is a crystalline compound with a molecular weight of approximately 328.28 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is reactive, particularly towards nucleophiles and reductants. It is stable under normal laboratory conditions but requires protection from light.

1-[4-(Benzyloxy)-3-nitrophenyl]ethanone is typically synthesized via a multistep process starting from benzoic acid. The reaction involves the formation of a benzyloxy derivative, followed by nitration, and then acetylation. The synthesis is carried out under mild conditions with good yields and selectivity.

1-[4-(Benzyloxy)-3-nitrophenyl]ethanone is used in pharmaceuticals for the synthesis of intermediates and in the polymer industry for the development of new materials. It also finds applications in the field of sensors and as a precursor in semiconductor manufacturing.

Handling 1-[4-(Benzyloxy)-3-nitrophenyl]ethanone requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a fume hood and away from light. In case of spill, it should be handled with absorbent material and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.