Compound Q&A
How is Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS: 176977-85-8) typically synthesized?
Answer
Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (CAS: 176977-85-8) is typically synthesized by reacting methyl 4-chloro-2-pyridinecarboxylate with hydrochloric acid. The reaction is conducted in a solvent such as dichloromethane or ethyl acetate, and the yield is usually around 85%. The use of a phase transfer catalyst can improve selectivity and yield.
About
CAS No
176977-85-8
English Name
Methyl 4-chloro-2-pyridinecarboxylate hydrochloride (1:1)
Molecular Formula
C7H7Cl2NO2
Molecular Weight
208.04399999999998 g/mol
SMILES
COC(=O)C1=NC=CC(=C1)Cl.Cl
InChIKey
PAGFSBPYVNFHAS-UHFFFAOYSA-N
Last Updated: 2025-10-23 07:31
