Phenyl 4-amino-2-hydroxybenzoate(CAS: 133-11-9)

Phenyl 4-amino-2-hydroxybenzoate (CAS: 133-11-9) is a white to off-white crystalline solid with a molecular weight of approximately 252.25 g/mol. It has a solubility of 1.5 g/L in water at 20°C. Chemically, it is slightly basic and exhibits weak reactivity in acidic conditions. It is soluble in common organic solvents like ethanol and acetone.

Phenyl 4-amino-2-hydroxybenzoate (CAS: 133-11-9) is typically synthesized via a condensation reaction between 4-amino-2-hydroxybenzoic acid and phenol. The reaction is catalyzed by a Lewis acid like aluminum chloride and usually proceeds with high yield. The product is then purified by recrystallization from hot water or ethanol.

Phenyl 4-amino-2-hydroxybenzoate (CAS: 133-11-9) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in polymer production as a stabilizer and in the development of sensors and semiconductors for electronic applications.

When handling Phenyl 4-amino-2-hydroxybenzoate (CAS: 133-11-9), appropriate personal protective equipment (PPE) such as gloves and goggles should be worn. It should be stored in a cool, dry place away from direct sunlight and heat sources. In case of spills, they should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.