Compound Q&A

How is Phenyl 4-amino-2-hydroxybenzoate (CAS: 133-11-9) typically synthesized?

Answer

Phenyl 4-amino-2-hydroxybenzoate
Phenyl 4-amino-2-hydroxybenzoate (CAS: 133-11-9) is typically synthesized via a condensation reaction between 4-amino-2-hydroxybenzoic acid and phenol. The reaction is catalyzed by a Lewis acid like aluminum chloride and usually proceeds with high yield. The product is then purified by recrystallization from hot water or ethanol.

About

CAS No 133-11-9
English Name Phenyl 4-amino-2-hydroxybenzoate
Molecular Formula C13H11NO3
Molecular Weight 229.24 g/mol
SMILES C1=CC=C(C=C1)OC(=O)C2=C(C=C(C=C2)N)O
InChIKey DNVVZWSVACQWJE-UHFFFAOYSA-N
Last Updated: 2026-03-10 14:55

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