Methyl 1,2,3,4-tetrahydro-6-isoquinolinecarboxylate(CAS: 185057-00-5)

CAS Number
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Basic Information
Molecular Formula
C11H13NO2
Molecular Weight
191.23 g/mol
Physical Properties
Boiling Point
330.2 °C at 760 mmHg
Flash Point
153.5 °C
Chemical Identifiers
SMILES
COC(=O)C1=CC2=C(CNCC2)C=C1
InChIKey
QFGFDECCVRJKHK-UHFFFAOYSA-N
Database References
MDL Number
MFCD09038210
FAQ
Methyl 1,2,3,4-tetrahydro-6-isoquinolinecarboxylate (CAS: 185057-00-5) is a solid crystalline compound with a molecular weight of approximately 227.23 g/mol. It is soluble in organic solvents such as ethanol and acetone. This compound is relatively stable under normal conditions but can undergo hydrolysis in acidic or basic media. Care must be taken when handling due to its potential reactivity.
How is Methyl 1,2,3,4-tetrahydro-6-isoquinolinecarboxylate (CAS: 185057-00-5) typically synthesized?
Methyl 1,2,3,4-tetrahydro-6-isoquinolinecarboxylate (CAS: 185057-00-5) can be synthesized through a multi-step reaction starting with 6-isoquinolinecarboxylic acid. This involves esterification with methanol under mild conditions using a catalytic amount of a strong acid like sulfuric acid. The yield and selectivity are typically high, making this a reliable method for preparing this compound.
Methyl 1,2,3,4-tetrahydro-6-isoquinolinecarboxylate (CAS: 185057-00-5) is used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It also finds applications in the polymer industry for developing functional materials. Additionally, it is used in the production of sensors and in semiconductor applications due to its chemical and physical properties.
When handling Methyl 1,2,3,4-tetrahydro-6-isoquinolinecarboxylate (CAS: 185057-00-5), proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It is advisable to work in a fume hood to minimize exposure. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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