2-(3-Bromophenyl)succinic acid(CAS: 69006-89-9)

2-(3-Bromophenyl)succinic acid is a white to off-white crystalline solid with a molecular weight of approximately 261.03 g/mol. It is slightly soluble in water and soluble in organic solvents like ethanol and acetone. Chemically, it is reactive due to the presence of the bromine atom and carboxylic acid group, which can participate in various chemical reactions such as esterification and substitution reactions.

2-(3-Bromophenyl)succinic acid is typically synthesized through a bromination reaction of 3-phenylpropionyl chloride with bromine in the presence of a phase transfer catalyst. The reaction yields the desired acid with good selectivity and purity. Commonly, this process is performed under reflux conditions in an organic solvent like dichloromethane.

2-(3-Bromophenyl)succinic acid is utilized in various industries, including pharmaceuticals, where it serves as a starting material for the synthesis of medicinal compounds. It is also used in the production of certain polymers and in sensor applications due to its chemical reactivity and functional groups.

When handling 2-(3-Bromophenyl)succinic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up using appropriate absorbent materials and followed by neutralization if necessary. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.