N-(3-Nitrophenyl)propionamide(CAS: 7470-50-0)

N-(3-Nitrophenyl)propionamide is a crystalline solid with a molecular weight of approximately 211.13 g/mol. It is slightly soluble in water but has good solubility in organic solvents like methanol and ethanol. Chemically, it is stable under normal conditions but can decompose at high temperatures. It reacts readily with bases and reducing agents.

N-(3-Nitrophenyl)propionamide is typically synthesized by the reaction of 3-nitrophenol with propionamide. This process usually involves the use of a solvent, such as methanol, and is carried out under acidic conditions. The yield is generally around 80-85%, and the reaction is selective, producing the desired product with high purity.

N-(3-Nitrophenyl)propionamide is used in various industries, particularly in pharmaceuticals for the synthesis of certain drugs. It also finds applications in the polymer industry as a stabilizer and in the production of semiconductors and sensors where its reactive properties are utilized.

When handling N-(3-Nitrophenyl)propionamide, it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and laboratory coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate materials, and the substance should be disposed of according to local regulations and SDS guidelines.