3-Bromo-2-pyridinecarboxylic acid(CAS: 30683-23-9)

3-Bromo-2-pyridinecarboxylic acid is a crystalline solid with a molecular weight of approximately 212.03 g/mol. It has a solubility of about 0.43 g/100 mL in water and is slightly soluble in ethanol. This compound is moderately reactive towards nucleophiles and is susceptible to hydrolysis under basic conditions. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

3-Bromo-2-pyridinecarboxylic acid can be synthesized through various methods, including bromination of 2-pyridinecarboxylic acid. One common method involves reacting 2-pyridinecarboxylic acid with bromine in the presence of a solvent such as pyridine. The reaction requires careful control of temperature and pH to ensure high yield and selectivity. The product can be isolated by recrystallization from an appropriate solvent.

3-Bromo-2-pyridinecarboxylic acid is used in various industries, particularly in pharmaceuticals and chemical synthesis. It serves as a precursor for the synthesis of other compounds and is utilized in the development of pharmaceuticals, specifically as a building block for drugs targeting various diseases. Additionally, it finds applications in the production of certain polymers and as a reagent in analytical chemistry.

When handling 3-Bromo-2-pyridinecarboxylic acid (CAS: 30683-23-9), it is essential to follow standard safety protocols. Wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure that the substance is handled in a well-ventilated area or a fume hood. Store it in a cool, dry place away from heat and direct sunlight. In case of a spill, immediately clean it up with appropriate absorbent materials and follow the emergency procedures outlined in the Safety Data Sheet (SDS).