3-Bromo-2-pyridinecarboxylic acid

Basic Information

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CAS Number

30683-23-9

Molecular Formula

C6H4BrNO2

Molecular Weight

202.01 g/mol

EINECS

639-403-7

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Off-White

Melting Point

141-1440C

Boiling Point

315.7±27.0 °C(Predicted)

Density

1.813

Flash Point

315.7 °C at 760 mmHg

Refractive Index

1.616

SMILES

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C1=CC(=C(N=C1)C(=O)O)Br

InChI

InChI=1S/C6H4BrNO2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,(H,9,10)

InChIKey

KBDIRPOTVAODSA-UHFFFAOYSA-N

LogP

1.5423

pKa

2.29±0.10(Predicted)

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

140

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

CS-W002771
AM20070088
3-Bromopyridine-2-carboxylic Acid
3-Bromopyridin-2-ylcarboxylic acid
3-bromo-2-pyridinecarboxylic acid
A5611
SY004667
2-Hydrazino-4-methyl-thiazole-5-carboxylicacidethylester
3-bromopicolinic acid
EN300-84427
3-Bromo-2-pyridine carboxylic acid
AF-399/40963066
SCHEMBL398923
3-BROMOPYRIDINE-2-CARBOXYLICACID
MFCD01320380
FT-0638933
J-400350
FS-1310
3-Bromo-pyridine-2-carboxylic acid
30683-23-9
3-Bromo-2-pyridinecarboxylic acid, AldrichCPR
bromopyridine carboxylic
J-512139
AKOS005198944
KBDIRPOTVAODSA-UHFFFAOYSA-N
2-Pyridinecarboxylic acid, 3-bromo-
3-bromo-2-pyridine carboxlic acid
3-Bromopicolinic acid pound>>2-Pyridinecarboxylic acid, 3-bromo-
F1926-0036
AC-3285
SB40495

MDL Number

MFCD01320380

EC Number

639-403-7

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Bromo-2-pyridinecarboxylic acid (CAS: 30683-23-9)?

3-Bromo-2-pyridinecarboxylic acid is a crystalline solid with a molecular weight of approximately 212.03 g/mol. It has a solubility of about 0.43 g/100 mL in water and is slightly soluble in ethanol. This compound is moderately reactive towards nucleophiles and is susceptible to hydrolysis under basic conditions. It is stable under normal conditions but should be stored in a cool, dry place to avoid degradation.

How is 3-Bromo-2-pyridinecarboxylic acid (CAS: 30683-23-9) typically synthesized?

3-Bromo-2-pyridinecarboxylic acid can be synthesized through various methods, including bromination of 2-pyridinecarboxylic acid. One common method involves reacting 2-pyridinecarboxylic acid with bromine in the presence of a solvent such as pyridine. The reaction requires careful control of temperature and pH to ensure high yield and selectivity. The product can be isolated by recrystallization from an appropriate solvent.

What industries use 3-Bromo-2-pyridinecarboxylic acid (CAS: 30683-23-9)?

3-Bromo-2-pyridinecarboxylic acid is used in various industries, particularly in pharmaceuticals and chemical synthesis. It serves as a precursor for the synthesis of other compounds and is utilized in the development of pharmaceuticals, specifically as a building block for drugs targeting various diseases. Additionally, it finds applications in the production of certain polymers and as a reagent in analytical chemistry.

What precautions should be taken when handling 3-Bromo-2-pyridinecarboxylic acid (CAS: 30683-23-9)?

When handling 3-Bromo-2-pyridinecarboxylic acid (CAS: 30683-23-9), it is essential to follow standard safety protocols. Wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Ensure that the substance is handled in a well-ventilated area or a fume hood. Store it in a cool, dry place away from heat and direct sunlight. In case of a spill, immediately clean it up with appropriate absorbent materials and follow the emergency procedures outlined in the Safety Data Sheet (SDS).