4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline(CAS: 122779-42-4)

4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline (CAS: 122779-42-4) is a white crystalline solid with a molecular weight of approximately 203.27 g/mol. It is slightly soluble in water and more soluble in organic solvents such as ethanol and acetone. The compound is reactive towards basic conditions and can undergo substitution reactions. It has a high boiling point and low volatility.

4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline is typically synthesized through an amination reaction of dimethylbenzylamine with (R)-1-bromoethylamine. The reaction is catalyzed by a Lewis acid such as aluminum chloride and proceeds with good selectivity and yield. The product is purified by recrystallization from ethanol.

4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline (CAS: 122779-42-4) is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It is also used in the semiconductor industry as a dopant and in the polymer industry for the preparation of functional polymers. Additionally, it finds application in the production of sensors and other electronic devices.

When handling 4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline (CAS: 122779-42-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up using absorbent materials and the area should be well-ventilated. Always consult a Safety Data Sheet (SDS) for detailed handling and disposal instructions.