Compound Q&A
How is 4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline (CAS: 122779-42-4) typically synthesized?
Answer
![4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline](https://static.chemtradehub.com/structs/122/122779-42-4-49e7.webp "4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline")
4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline is typically synthesized through an amination reaction of dimethylbenzylamine with (R)-1-bromoethylamine. The reaction is catalyzed by a Lewis acid such as aluminum chloride and proceeds with good selectivity and yield. The product is purified by recrystallization from ethanol.
About
CAS No
122779-42-4
English Name
4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline
Molecular Formula
C10H16N2
Molecular Weight
164.25 g/mol
SMILES
CC(C1=CC=C(C=C1)N(C)C)N.Cl.Cl
InChIKey
VDOKYXHLVQGSJQ-MRVPVSSYSA-N
Last Updated: 2025-12-25 18:29
![4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}
![4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![4-[(1R)-1-Aminoethyl]-N,N-dimethylaniline — ShangHaiYiJiShengWuKeJiYouXianGongSiXiaoShouBu](https://static.chemtradehub.com/suppliers/67cecfe92b2de6e8e95a656d/67cecfe92b2de6e8e95a656d-logo.webp){kind=logo}