3-Bromo-4-pyridinethiol(CAS: 82264-72-0)

3-Bromo-4-pyridinethiol (CAS: 82264-72-0) is a crystalline solid with a molecular weight of approximately 196.02 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. The compound is moderately reactive and undergoes substitution reactions. It has a characteristic odor and is sensitive to heat and light.

3-Bromo-4-pyridinethiol can be synthesized by the reaction of 4-pyridinethiol with bromine in the presence of a suitable solvent. Common solvents include dichloromethane or ethanol. The reaction is carried out at room temperature, and the use of a catalyst such as iron(III) chloride can improve the yield and selectivity. The overall reaction is highly exothermic and requires careful handling to prevent the formation of unwanted by-products.

3-Bromo-4-pyridinethiol (CAS: 82264-72-0) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those involving sulfur-containing functionalities. It is also utilized in the production of sensors for detecting various gases and in the development of organic semiconductors for electronic devices. Additionally, it plays a role in the manufacturing of some polymers with specific chemical properties.

When handling 3-Bromo-4-pyridinethiol (CAS: 82264-72-0), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from sources of heat and light. Working with it should be done in a fume hood to minimize inhalation risks. In case of a spill, it is recommended to use appropriate absorbent materials and dispose of them according to local regulations. Always refer to the safety data sheet (SDS) for specific handling and disposal instructions.