4-{4-[(Methylsulfonyl)amino]phenyl}-4-oxobutanoic acid(CAS: 100632-57-3)

4-{4-[(Methylsulfonyl)amino]phenyl}-4-oxobutanoic acid (CAS: 100632-57-3) is a white crystalline solid with a molecular weight of approximately 332.46 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is reactive towards bases and can undergo hydrolysis under basic conditions. It also exhibits acidity due to the carboxylic acid group.

4-{4-[(Methylsulfonyl)amino]phenyl}-4-oxobutanoic acid (CAS: 100632-57-3) is typically synthesized via the condensation of 4-(methylsulfonylamino)benzoic acid with acryloyl chloride, followed by hydrolysis. The reaction is catalyzed by a Lewis acid like aluminum chloride. Yield and selectivity are good, with minimal by-products.

4-{4-[(Methylsulfonyl)amino]phenyl}-4-oxobutanoic acid (CAS: 100632-57-3) is used in the pharmaceutical industry for its potential as a drug intermediate. It is also relevant in the polymer industry for modifying properties and in sensor technology due to its functional groups.

When handling 4-{4-[(Methylsulfonyl)amino]phenyl}-4-oxobutanoic acid (CAS: 100632-57-3), wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store the compound in a cool, dry place, away from heat and direct sunlight. Handle in a fume hood to avoid inhalation and skin contact. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.