5-Hydroxy-2(1H)-quinolinone

Basic Information

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CAS Number

31570-97-5

Molecular Formula

C9H7NO2

Molecular Weight

161.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

>300°C

Boiling Point

402.4°C at 760 mmHg

SMILES

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C1=CC2=C(C=CC(=O)N2)C(=C1)O

InChI

InChI=1S/C9H7NO2/c11-8-3-1-2-7-6(8)4-5-9(12)10-7/h1-5,11H,(H,10,12)

InChIKey

XOXGLLQTNQBDKL-UHFFFAOYSA-N

LogP

1.2336999999999998

Topological Polar Surface Area

53.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

225

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Q27121429
J-517622
5-hydroxy-2-quinolone
BCP24371
5-HYDROXY-1,2-DIHYDROQUINOLIN-2-ONE
5-Hydroxy-quinolin-2(1H)-one
XOXGLLQTNQBDKL-UHFFFAOYSA-N
AKOS005072168
5-hydroxyquinolin-2(1H)-one
MFCD02181132
AM807161
SY110039
31570-97-5
MB02360
5-hydroxyquinolone
5-Hydroxy-2(1H)-quinolinone
DTXSID40419213
5-hydroxycarbostyril
FT-0670096
A820913
quinoline-2,5-diol
5-hydroxy-1H-quinolin-2-one
CHEBI:48995
5-oxidanyl-1H-quinolin-2-one
CS-W004487
2(1H)-Quinolinone, 5-hydroxy-
Z1198306810
NSC-134652
DA-0923
EN300-170399
NSC134652

MDL Number

MFCD02181132

Customs Code

2933790090

FAQ

What are the physical and chemical properties of 5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5)?

5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5) is a crystalline compound with a molecular weight of approximately 191.18 g/mol. It has a solubility of about 10.6 mg/L in water. This compound is moderately reactive and can undergo various chemical transformations. It forms a white crystalline powder at room temperature and is stable under normal storage conditions.

How is 5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5) typically synthesized?

5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5) is typically synthesized through the condensation reaction of 2-amino-1,4-naphthoquinone with hydrazine hydrate, followed by oxidation of the resulting hydrazide. This process yields the target compound with good yield and selectivity. The reaction is catalyzed by oxalic acid or similar reagents.

What industries use 5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5)?

5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5) is used in pharmaceuticals for the synthesis of certain drug intermediates. It is also utilized in the development of sensors and semiconductors due to its unique electronic properties. The compound is less commonly used in polymer synthesis but finds applications in specific areas requiring its specific chemical functionality.

What precautions should be taken when handling 5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5)?

When handling 5-Hydroxy-2(1H)-quinolinone (CAS: 31570-97-5), it is important to wear appropriate personal protective equipment (PPE) such as safety glasses, gloves, and lab coat. Work should be conducted in a well-ventilated area or a fume hood. Proper spill handling procedures should be followed, and the material safety data sheet (MSDS) should be consulted for specific guidelines. Store the compound in a cool, dry place away from direct sunlight and flammable materials.