(2-Chloro-3-nitrophenyl)methanol(CAS: 89639-98-5)

(2-Chloro-3-nitrophenyl)methanol is a crystalline solid at room temperature with a molecular weight of approximately 218.01 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly with nucleophiles and reductants, making it useful in organic synthesis.

(2-Chloro-3-nitrophenyl)methanol can be synthesized by the reaction of 2-chloro-3-nitrobenzaldehyde with methanol in the presence of a strong acid catalyst like sulfuric acid. The process involves esterification, followed by reduction to form the alcohol. Yield and selectivity can be optimized with appropriate reaction conditions and catalysts.

(2-Chloro-3-nitrophenyl)methanol finds applications in pharmaceuticals for the synthesis of intermediates and drug molecules. It is also used in the production of dyes and pigments, as a chemical reagent in analytical chemistry, and in the manufacture of organic electronics and semiconductors.

Proper personal protective equipment (PPE) should be worn when handling (2-Chloro-3-nitrophenyl)methanol, including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood. Spills should be handled with caution using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.