5-Fluoro-2-pyridinecarbaldehyde(CAS: 31181-88-1)

5-Fluoro-2-pyridinecarbaldehyde (CAS: 31181-88-1) is a white crystalline solid with a molecular weight of 148.06 g/mol. It has a low solubility in water (0.2 g/L at 20°C) but is more soluble in organic solvents like ethanol and acetone. It is reactive towards nucleophiles and can undergo condensation reactions. This compound is often used in organic synthesis and pharmaceuticals.

5-Fluoro-2-pyridinecarbaldehyde (CAS: 31181-88-1) can be synthesized from 2-pyridinecarbaldehyde using fluoroform (CHF3) in the presence of a base like potassium tert-butoxide. The reaction is typically carried out in anhydrous conditions to minimize side reactions, ensuring high selectivity and good yield.

5-Fluoro-2-pyridinecarbaldehyde (CAS: 31181-88-1) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in the polymer industry for the development of new materials and in the sensor technology sector for creating chemical sensors.

When handling 5-Fluoro-2-pyridinecarbaldehyde (CAS: 31181-88-1), it is important to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. Spills should be cleaned up using appropriate absorbent materials and the area should be ventilated. Always consult the Safety Data Sheet (SDS) for detailed handling and safety information.