2-Chloro-4,6-dimethylpyridine

Basic Information

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CAS Number

30838-93-8

Molecular Formula

C7H8ClN

Molecular Weight

141.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

208.1℃ at 760 mmHg

Density

1.114

Water Solubility

Slightly soluble in water.

Flash Point

99.1℃

Refractive Index

1.524

SMILES

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CC1=CC(=NC(=C1)Cl)C

InChI

InChI=1S/C7H8ClN/c1-5-3-6(2)9-7(8)4-5/h3-4H,1-2H3

InChIKey

COVGXNSRDOYAJD-UHFFFAOYSA-N

LogP

2.35184

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

94.9

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

2-Chloro-4,6-lutidine
AKOS005063648
Pyridine, 2-chloro-4,6-dimethyl-
MFCD08277279
SCHEMBL390280
AMY7895
A5633
2-chloro-4,6-dimethyl-pyridine
W-202277
EN300-94218
DTXSID20500794
PS-4818
2-Chloro-4,6-dimethylpyridine
DS-1155
2-Chloro-4,6-dimethyl pyridine
30838-93-8
FT-0658374
CS-D0983
COVGXNSRDOYAJD-UHFFFAOYSA-N
SY005475
AC-1137
2-Chlor-4,6-dimethyl-nicotinonitril
2-Chlor-4,6-dimethylpyridin
2-Chlor-4.6-lutidin
6-Chloro-2,4-lutidine
2,4-Lutidine,6-chloro- (8CI)

MDL Number

MFCD08277279

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Chloro-4,6-dimethylpyridine (CAS: 30838-93-8)?

2-Chloro-4,6-dimethylpyridine has a crystalline form at room temperature. Its molecular weight is approximately 190.6 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can react with strong bases to form pyridine derivatives. It is used as a precursor in organic synthesis and has limited reactivity under normal conditions.

How is 2-Chloro-4,6-dimethylpyridine (CAS: 30838-93-8) typically synthesized?

2-Chloro-4,6-dimethylpyridine is typically synthesized through the reaction of 4,6-dimethylpyridine with chlorine gas in the presence of a Lewis acid catalyst such as aluminum chloride. The process yields a high purity product with good selectivity. The reaction is carried out under anhydrous conditions to avoid hydrolysis, and the yield can be up to 90%.

What industries use 2-Chloro-4,6-dimethylpyridine (CAS: 30838-93-8)?

2-Chloro-4,6-dimethylpyridine is primarily used in the pharmaceutical industry as a precursor for the synthesis of various drugs. It also finds applications in the polymer industry for the production of certain types of plastics and in the semiconductor industry as a component in organic light-emitting diodes (OLEDs). Its use in sensors is also reported, though less common.

What precautions should be taken when handling 2-Chloro-4,6-dimethylpyridine (CAS: 30838-93-8)?

When handling 2-Chloro-4,6-dimethylpyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate methods, and the area should be thoroughly cleaned with water. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.