Methyl N-Cbz-piperidine-2-carboxylate(CAS: 180609-56-7)

Methyl N-Cbz-piperidine-2-carboxylate (CAS: 180609-56-7) is a crystalline solid with a molecular weight of approximately 300.35 g/mol. It has a low solubility in water but is soluble in organic solvents such as dichloromethane and acetonitrile. Chemically, it is moderately reactive towards nucleophiles and is often used as a precursors in organic synthesis. It exhibits good stability under normal storage conditions but should be handled with caution to avoid decomposition under strong acidic or basic conditions.

Methyl N-Cbz-piperidine-2-carboxylate (CAS: 180609-56-7) is commonly synthesized through the condensation of piperidine-2-carboxylic acid with benzyl chloroformate. The reaction is typically conducted in the presence of a base such as triethylamine. The benzyl protecting group is used to facilitate further functionalization steps in synthetic routes. This method provides good yields and high regioselectivity.

Methyl N-Cbz-piperidine-2-carboxylate (CAS: 180609-56-7) is primarily used in the pharmaceutical and fine chemical industries. It serves as a valuable intermediate in the synthesis of various drugs and bioactive molecules. Additionally, it is employed in the development of novel materials, such as sensors and semiconductors, due to its structural versatility and reactivity.

When handling Methyl N-Cbz-piperidine-2-carboxylate (CAS: 180609-56-7), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately cleaned up with appropriate absorbents. For detailed safety information, refer to the Safety Data Sheet (SDS) which provides comprehensive guidelines on handling and storage.