Perampanel Impurity 8

Basic Information

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CAS Number

172732-52-4

Molecular Formula

C10H10BNO2

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

47.0 to 51.0 deg-C

Boiling Point

372.4°C at 760 mmHg

SMILES

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B1(OCCCO1)C2=CC=CC=C2C#N

InChI

InChI=1S/C10H10BNO2/c12-8-9-4-1-2-5-10(9)11-13-6-3-7-14-11/h1-2,4-5H,3,6-7H2

InChIKey

REQZFVYFYAZUMG-UHFFFAOYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

232

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

C2993
2-Cyanophenylboronic acid 1,3-propanediol ester
2-cyanophenyl boronicacid 1,3-propanediol ester
2-(1,3,2-Dioxaborinane-2-yl)benzonitrile
BCP11356
2-Cyanophenylboronic acid propanediol ester
AKOS004116216
2-Cyanophenylboronic acid 1,3-propanediol cyclic ester
SCHEMBL687490
Benzonitrile,2-(1,3,2-dioxaborinan-2-yl)-
2-CYANOPHENYLBORONIC ACID, 1,3-PROPANEDIOL CYCLIC ESTER
DTXSID80393361
172732-52-4
FT-0688804
CS-W000883
Perampanel intermediate
J-010845
7-Amino-2,4-difluoro-9H-fluoren-9-one
A851850
AC-33890
2-(2-Cyanophenyl)-1,3,2-dioxaborinane
SY051086
REQZFVYFYAZUMG-UHFFFAOYSA-N
2-CYANOBENZENEBORONIC ACID 1,3-PROPANEDIOL ESTER
AB17250
(2-CYANOPHENYL)BORONIC ACID, 1,3-PROPANEDIOL CYCLIC ESTER
2-Cyanophenylboronic acid 13-propanediol cyclic ester
2-(1,3,2-dioxaborinan-2-yl)benzonitrile
MFCD04039012
AS-18695
Benzonitrile, 2-(1,3,2-dioxaborinan-2-yl)-

MDL Number

MFCD04039012

Customs Code

2934999090

FAQ

What regulatory guidelines apply to Perampanel Impurity 8 (CAS: 172732-52-4)?

Perampanel Impurity 8 (CAS: 172732-52-4) should comply with the regulatory guidelines for pharmaceutical impurities under the REACH regulations in the EU, and FDA/EPA requirements in the United States. It is classified as a pharmaceutical substance and should follow Good Manufacturing Practices (GMP) and other relevant safety and environmental regulations.

Are there alternatives to Perampanel Impurity 8 (CAS: 172732-52-4) in synthesis?

While Perampanel Impurity 8 (CAS: 172732-52-4) is a specific impurity in the synthesis of perampanel, other analogs or isomers can be used as alternatives. Common substitutes include isomers of perampanel itself or other related compounds that can serve similar roles in the formulation of anticonvulsant drugs.

What is the market or research trend for Perampanel Impurity 8 (CAS: 172732-52-4)?

The market for Perampanel Impurity 8 (CAS: 172732-52-4) is closely tied to the broader market for perampanel, an anticonvulsant drug. Research trends indicate a focus on developing more potent and less impure versions of perampanel, which will likely reduce the need for this specific impurity. Additionally, there is increasing emphasis on drug safety and purity in clinical trials and commercial products.

How should waste containing Perampanel Impurity 8 (CAS: 172732-52-4) be handled?

Waste containing Perampanel Impurity 8 (CAS: 172732-52-4) should be collected in appropriate containers and disposed of through professional waste disposal services that are compliant with environmental protection regulations. Incineration is a common method, and environmental precautions include ensuring no hazardous emissions are released into the atmosphere, and proper storage to prevent environmental contamination before disposal.