Methyl 4-acetyl-2-hydroxybenzoate(CAS: 27475-11-2)

Methyl 4-acetyl-2-hydroxybenzoate (CAS: 27475-11-2) is a white to pale yellow crystalline solid with a molecular weight of approximately 218.22 g/mol. It is slightly soluble in water and soluble in organic solvents such as ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo ester hydrolysis under basic conditions. It is less reactive towards acid-catalyzed hydrolysis.

Methyl 4-acetyl-2-hydroxybenzoate (CAS: 27475-11-2) is typically synthesized via esterification of acetic anhydride and 4-hydroxybenzoic acid. The reaction is usually conducted in the presence of a catalyst such as sulfuric acid, and yields up to 90% of the desired product. The product can be purified by recrystallization from ethanol.

Methyl 4-acetyl-2-hydroxybenzoate (CAS: 27475-11-2) is used in the pharmaceutical industry for synthesizing intermediates and APIs, in the polymer industry as a plasticizer, and in the sensor industry for detecting specific compounds. It is also utilized in the semiconductor industry as a resist material in photolithography processes.

When handling Methyl 4-acetyl-2-hydroxybenzoate (CAS: 27475-11-2), ensure the use of appropriate personal protective equipment (PPE) such as gloves and safety glasses. Work in a well-ventilated area or in a fume hood to minimize inhalation risk. In case of spill, neutralize any acid present and dispose of the material according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.