4-Bromo-2-fluoro-6-iodoaniline(CAS: 1201149-19-0)

4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is a crystalline solid. Its molecular weight is approximately 355.2 g/mol. It has limited solubility in water but is more soluble in organic solvents like acetone and dichloromethane. The compound is known for its high reactivity, particularly in nucleophilic aromatic substitution reactions.

4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is typically synthesized through a multistep process involving bromination and fluorination of aniline followed by iodination. Common methods include the use of N-bromosuccinimide (NBS) or N-iodosuccinimide (NIS) in the presence of a base like sodium carbonate, with subsequent iodination using iodine in the presence of a Lewis acid like aluminum chloride (AlCl3).

4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the semiconductor industry for the production of photoresists. It is also utilized in the development of novel materials for sensors and in the preparation of organic compounds for research purposes.

Proper handling of 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood, and proper spill cleanup procedures should be followed. Always refer to the safety data sheet (SDS) for detailed instructions on handling and disposal.