4-Bromo-2-fluoro-6-iodoaniline | CAS No. 1201149-19-0
4-Bromo-2-fluoro-6-iodoaniline
Basic Information
CAS Number
1201149-19-0
Molecular Formula
C6H4BrFIN
Molecular Weight
315.91 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 4-Bromo-2-fluoro-6-iodoaniline
- 4-Bromo-2-fluoro-6-iodo-phenylamine
- Benzenamine, 4-bromo-2-fluoro-6-iodo-
MDL Number
MFCD22570400
Customs Code
2921420090
FAQ
What are the physical and chemical properties of 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0)?
4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is a crystalline solid. Its molecular weight is approximately 355.2 g/mol. It has limited solubility in water but is more soluble in organic solvents like acetone and dichloromethane. The compound is known for its high reactivity, particularly in nucleophilic aromatic substitution reactions.
How is 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) typically synthesized?
4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is typically synthesized through a multistep process involving bromination and fluorination of aniline followed by iodination. Common methods include the use of N-bromosuccinimide (NBS) or N-iodosuccinimide (NIS) in the presence of a base like sodium carbonate, with subsequent iodination using iodine in the presence of a Lewis acid like aluminum chloride (AlCl3).
What industries use 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0)?
4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is used in the pharmaceutical industry for the synthesis of certain drugs, as well as in the semiconductor industry for the production of photoresists. It is also utilized in the development of novel materials for sensors and in the preparation of organic compounds for research purposes.
What precautions should be taken when handling 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0)?
Proper handling of 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood, and proper spill cleanup procedures should be followed. Always refer to the safety data sheet (SDS) for detailed instructions on handling and disposal.
Related Compounds
![N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}ornithine structure](https://static.chemtradehub.com/structs/118/118476-89-4-a153.webp "N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}ornithine structure")
N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~5~-{[(2-methyl-2-propanyl)oxy]carbonyl}ornithine
CAS Number:
118476-89-4
Molecular Formula:
C25H30N2O6
3-(2-Chlorophenyl)-6-(2,6-difluorophenyl)-1,2,4,5-tetrazine
CAS Number:
162320-67-4
Molecular Formula:
C14H7ClF2N4
![Zirconium(4+) tetrakis[ethyl(methyl)azanide] structure](https://static.chemtradehub.com/structs/175/175923-04-3-d680.webp "Zirconium(4+) tetrakis[ethyl(methyl)azanide] structure")
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