Compound Q&A

How is 4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) typically synthesized?

Answer

4-Bromo-2-fluoro-6-iodoaniline
4-Bromo-2-fluoro-6-iodoaniline (CAS: 1201149-19-0) is typically synthesized through a multistep process involving bromination and fluorination of aniline followed by iodination. Common methods include the use of N-bromosuccinimide (NBS) or N-iodosuccinimide (NIS) in the presence of a base like sodium carbonate, with subsequent iodination using iodine in the presence of a Lewis acid like aluminum chloride (AlCl3).

About

English Name 4-Bromo-2-fluoro-6-iodoaniline
Molecular Formula C6H4BrFIN
Molecular Weight 315.91099999999994 g/mol
SMILES Nc1c(F)cc(Br)cc1I
InChIKey BEVNAVSJFOFMKX-UHFFFAOYSA-N
Last Updated: 2026-03-10 23:59

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