(1R,2S)-2-Aminocyclohexanol hydrochloride (1:1)(CAS: 6936-47-6)

(1R,2S)-2-Aminocyclohexanol hydrochloride (CAS: 6936-47-6) is a crystalline compound with a molecular weight of approximately 148.68 g/mol. It has a pKa of about 8.4 and is slightly soluble in water. The compound is known for its reactivity with bases, making it useful in various chemical reactions. It is also stable under normal conditions but should be stored in a cool, dry place to maintain its stability.

(1R,2S)-2-Aminocyclohexanol hydrochloride (CAS: 6936-47-6) is typically synthesized via the hydrogenation of 2-chlorocyclohexanol followed by reaction with ammonia. This process leads to a high yield and good selectivity towards the (1R,2S) configuration. Commonly used catalysts include palladium on carbon under hydrogen pressure. The reaction is carried out under mild conditions, ensuring a safe and efficient process.

(1R,2S)-2-Aminocyclohexanol hydrochloride (CAS: 6936-47-6) is commonly used in the pharmaceutical industry for the synthesis of various drugs due to its amine functionality. It also finds applications in the polymer industry for the modification of plastics and in the semiconductor industry for the production of precursors. Additionally, it is used in the fragrance industry to impart specific odor characteristics in perfumes and cosmetics.

When handling (1R,2S)-2-Aminocyclohexanol hydrochloride (CAS: 6936-47-6), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. The substance should be handled in a well-ventilated area or under a fume hood to minimize inhalation risks. In case of a spill, neutralize any acidic residues with a base and dispose of the waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.