Compound Q&A
How is (1R,2S)-2-Aminocyclohexanol hydrochloride (CAS: 6936-47-6) typically synthesized?
Answer
(1R,2S)-2-Aminocyclohexanol hydrochloride (CAS: 6936-47-6) is typically synthesized via the hydrogenation of 2-chlorocyclohexanol followed by reaction with ammonia. This process leads to a high yield and good selectivity towards the (1R,2S) configuration. Commonly used catalysts include palladium on carbon under hydrogen pressure. The reaction is carried out under mild conditions, ensuring a safe and efficient process.
About
CAS No
6936-47-6
English Name
(1R,2S)-2-Aminocyclohexanol hydrochloride (1:1)
Molecular Formula
C6H14ClNO
Molecular Weight
151.63 g/mol
SMILES
C1CCC(C(C1)N)O.Cl
InChIKey
LKKCSUHCVGCGFA-RIHPBJNCSA-N
Last Updated: 2025-10-29 13:16
