Ethyl 2-fluoro-5-iodobenzoate(CAS: 773136-66-6)

Ethyl 2-fluoro-5-iodobenzoate (CAS: 773136-66-6) is a crystalline compound with a molecular weight of approximately 333.03 g/mol. It has a high solubility in organic solvents like methanol and acetone but is only slightly soluble in water. Chemically, it is relatively stable but can react with bases. It is typically stored at room temperature and away from humid environments.

Ethyl 2-fluoro-5-iodobenzoate (CAS: 773136-66-6) can be synthesized through a multi-step process involving the initial formation of 2-fluoro-5-iodobenzoic acid followed by its esterification with ethanol. The synthesis typically uses thionyl chloride as an acylating agent and requires careful control of reaction conditions to achieve high yields and selectivity.

Ethyl 2-fluoro-5-iodobenzoate (CAS: 773136-66-6) is primarily used in pharmaceutical and chemical industries for the synthesis of intermediates and active pharmaceutical ingredients. It also finds applications in the production of certain polymers and in analytical chemistry for reagent development.

When handling Ethyl 2-fluoro-5-iodobenzoate (CAS: 773136-66-6), it is essential to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat. Operations should be conducted in a well-ventilated area or fume hood due to its volatility. Spills should be handled carefully, and the material safety data sheet (MSDS) should be consulted for detailed spill procedures and emergency response information.