6-Chloro-3,4-pyridinedicarboxylic acid(CAS: 243835-70-3)

6-Chloro-3,4-pyridinedicarboxylic acid (CAS: 243835-70-3) is a crystalline solid with a molecular weight of approximately 175.03 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it exhibits typical carboxylic acid properties, including reactivity with bases and nucleophiles. It can undergo esterification, amide formation, and other reactions characteristic of dicarboxylic acids.

6-Chloro-3,4-pyridinedicarboxylic acid (CAS: 243835-70-3) can be synthesized via the chlorination of 3,4-pyridinedicarboxylic acid using thionyl chloride as the chlorinating agent. The reaction typically occurs in a solvent like dichloromethane, and the process is conducted under anhydrous conditions to ensure high yield and selectivity. Additional purification steps, such as recrystallization, may be required to obtain the desired purity.

6-Chloro-3,4-pyridinedicarboxylic acid (CAS: 243835-70-3) is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It also finds applications in the polymer industry for the production of functional polymers and in the electronics industry for the fabrication of semiconductor materials. Additionally, it has potential uses in the development of sensors and as a precursor in various organic synthesis reactions.

When handling 6-Chloro-3,4-pyridinedicarboxylic acid (CAS: 243835-70-3), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to the compound. Spills should be cleaned up immediately using appropriate methods, and proper disposal procedures should be followed. Always consult the Safety Data Sheet (SDS) for detailed guidelines on safe handling and storage.