2-((2,2-Dimethylpropanoyl)amino)-2-(4-hydroxyphenyl)acetic acid, (2R)-(CAS: 205826-86-4)

CAS Number
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Other Suppliers for 2-((2,2-Dimethylpropanoyl)amino)-2-(4-hydroxyphenyl)acetic acid, (2R)-
Basic Information
Molecular Formula
C13H17NO4
Molecular Weight
251.28 g/mol
Chemical Identifiers
SMILES
CC(C)(C)C(=O)NC(C1=CC=C(C=C1)O)C(=O)O
InChIKey
BSXQHKOBFTYRJX-SNVBAGLBSA-N
Database References
MDL Number
MFCD24682763
FAQ
The compound is a white crystalline solid with a molecular weight of approximately 284.37 g/mol. It is slightly soluble in water and has a pKa of about 4.1. The compound is reactive towards bases and can undergo hydrolysis under basic conditions. It is also sensitive to oxidative conditions.
The compound is synthesized via the condensation of 2,2-dimethylpropionyl chloride with 4-hydroxyphenylacetic acid. The reaction is catalyzed by an organic base like triethylamine and is performed in an aqueous solvent. The yield is typically around 70-80% with good selectivity towards the (2R)-stereoisomer.
This compound is used in the pharmaceutical industry for the development of certain drug candidates. It is also utilized in the polymer industry as a monomer for the synthesis of specialty polymers. Additionally, it finds applications in the sensor industry for the development of new biosensors.
Proper Personal Protective Equipment (PPE) including gloves, lab coat, and safety goggles should be worn when handling this compound. It should be stored in a cool, dry place away from direct sunlight and should be handled in a well-ventilated area or fume hood. In the event of a spill, it should be handled according to the Material Safety Data Sheet (SDS) guidelines.
Safety Notice
Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.
Always follow proper handling procedures
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