Compound Q&A
How is 2-((2,2-Dimethylpropanoyl)amino)-2-(4-hydroxyphenyl)acetic acid, (2R)- (CAS: 205826-86-4) typically synthesized?
Answer
The compound is synthesized via the condensation of 2,2-dimethylpropionyl chloride with 4-hydroxyphenylacetic acid. The reaction is catalyzed by an organic base like triethylamine and is performed in an aqueous solvent. The yield is typically around 70-80% with good selectivity towards the (2R)-stereoisomer.
About
CAS No
205826-86-4
English Name
2-((2,2-Dimethylpropanoyl)amino)-2-(4-hydroxyphenyl)acetic acid, (2R)-
Molecular Formula
C13H17NO4
Molecular Weight
251.28199999999998 g/mol
SMILES
CC(C)(C)C(=O)NC(C1=CC=C(C=C1)O)C(=O)O
InChIKey
BSXQHKOBFTYRJX-SNVBAGLBSA-N
Last Updated: 2025-11-07 19:01
