4-Bromo-1-benzothiophene-2-carboxylic acid(CAS: 5194-37-6)

4-Bromo-1-benzothiophene-2-carboxylic acid (CAS: 5194-37-6) has a crystalline form and a molecular weight of approximately 269.02 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetonitrile. Chemically, it is reactive, particularly towards nucleophiles and electrophiles, and is often used in synthetic chemistry due to its bromine substituent.

4-Bromo-1-benzothiophene-2-carboxylic acid (CAS: 5194-37-6) is typically synthesized by bromination of 1-benzothiophene-2-carboxylic acid using N-bromosuccinimide (NBS) in an appropriate solvent like dichloromethane (DCM). The reaction is usually conducted under light or heat and is highly selective for the bromination at the desired position.

4-Bromo-1-benzothiophene-2-carboxylic acid (CAS: 5194-37-6) is used in various industries, particularly in pharmaceuticals and materials science. It serves as a key intermediate for the development of new drugs and is also employed in the synthesis of sensors and semiconductors due to its unique chemical properties.

When handling 4-Bromo-1-benzothiophene-2-carboxylic acid (CAS: 5194-37-6), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood and ensure proper ventilation. Spills should be cleaned up carefully, and consult the Safety Data Sheet (SDS) for specific instructions. This compound may cause irritation and should be handled with care to avoid exposure.