Diethyl 2-(2-oxopropyl)succinate(CAS: 1187-74-2)

Diethyl 2-(2-oxopropyl)succinate (CAS: 1187-74-2) is a colorless or slightly yellow crystalline compound with a molecular weight of approximately 238.32 g/mol. It is sparingly soluble in water and soluble in common organic solvents like ethanol and acetone. It exhibits moderate reactivity, particularly in ester exchange reactions and esterification processes.

Diethyl 2-(2-oxopropyl)succinate (CAS: 1187-74-2) can be synthesized via esterification of 2-(2-oxopropyl)succinic acid with diethyl acetate. The reaction is typically catalyzed by strong acids such as concentrated sulfuric acid. The yield is generally high, and the product can be isolated by conventional techniques including recrystallization.

Diethyl 2-(2-oxopropyl)succinate (CAS: 1187-74-2) is used in various industries. It serves as a key intermediate in the production of pharmaceuticals, where it is utilized in the synthesis of active pharmaceutical ingredients. It also finds applications in polymer production, particularly in the synthesis of thermosetting resins, and in sensor technology and semiconductor manufacturing as a precursor for certain functional groups.

When handling Diethyl 2-(2-oxopropyl)succinate (CAS: 1187-74-2), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be carefully cleaned up, and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.