4-Bromo-2-methyl-1-nitrobenzene(CAS: 52414-98-9)

4-Bromo-2-methyl-1-nitrobenzene (CAS: 52414-98-9) is a crystalline compound with a molecular weight of approximately 229.04 g/mol. It has a melting point of 124-125°C and is slightly soluble in water. This compound is known for its high reactivity, particularly towards nucleophilic substitution and reduction reactions.

4-Bromo-2-methyl-1-nitrobenzene (CAS: 52414-98-9) is typically synthesized by bromination of 2-methyl-1-nitrobenzene followed by purification. Common methods include the use of N-bromosuccinimide (NBS) as the brominating agent in an inert solvent like benzene or toluene under light or heat. The yield is usually around 70-80%, with high selectivity for the bromination reaction.

4-Bromo-2-methyl-1-nitrobenzene (CAS: 52414-98-9) is used in the pharmaceutical industry for the synthesis of various drug intermediates, and in the polymer industry for the development of functional polymers. It also finds applications in the sensor and semiconductor industries, particularly in the preparation of derivatized compounds for specific sensing applications.

When handling 4-Bromo-2-methyl-1-nitrobenzene (CAS: 52414-98-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a laboratory coat. Work should be conducted in a fume hood to minimize exposure. Spills should be carefully cleaned up using appropriate absorbent materials, and the area should be ventilated. Refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.