Methyl (3r)-3-amino-4-(2,4,5-trifluorophenyl)butanoate(CAS: 881995-69-3)

Methyl (3r)-3-amino-4-(2,4,5-trifluorophenyl)butanoate (CAS: 881995-69-3) is a crystalline compound with a molecular weight of approximately 281.07 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and acetone. This compound is reactive, particularly with nucleophiles due to the amino group, and can undergo substitution reactions. It exhibits moderate reactivity in acidic and basic conditions.

Methyl (3r)-3-amino-4-(2,4,5-trifluorophenyl)butanoate (CAS: 881995-69-3) is typically synthesized via a multi-step process involving the bromination of 2,4,5-trifluorobenzyl alcohol, followed by nucleophilic substitution with methylamine. This process utilizes a phase transfer catalyst and occurs in polar aprotic solvents. The yield is generally moderate to good, and the selectivity is high due to the steric strain in the 3r configuration.

Methyl (3r)-3-amino-4-(2,4,5-trifluorophenyl)butanoate (CAS: 881995-69-3) is primarily used in the pharmaceutical industry for the synthesis of drugs targeting various diseases. It also finds applications in the polymer industry for the development of functional polymers with improved properties. Additionally, it can be used in the production of sensors and semiconductors due to its unique chemical properties.

When handling Methyl (3r)-3-amino-4-(2,4,5-trifluorophenyl)butanoate (CAS: 881995-69-3), proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of fumes. Spills should be cleaned up with care, using appropriate absorbents and disposing of waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.