4-Chloro-7-fluoro-3-iodo-6-methoxyquinoline(CAS: 1602859-53-9)

4-Chloro-7-fluoro-3-iodo-6-methoxyquinoline is a solid with a crystalline form. The molecular weight is approximately 405.09 g/mol. It is slightly soluble in water and highly soluble in organic solvents like methanol and DMF. The compound is known for its reactivity, particularly in nucleophilic substitution reactions.

4-Chloro-7-fluoro-3-iodo-6-methoxyquinoline is typically synthesized through a multistep process involving the introduction of chlorine, iodine, and methoxy groups onto the quinoline ring. Common reagents include iodine and methanol, with the use of Lewis acids as catalysts. The yield and selectivity of the reaction can range depending on the specific conditions.

4-Chloro-7-fluoro-3-iodo-6-methoxyquinoline is primarily used in the pharmaceutical industry, where it serves as a precursor for drug synthesis. It is also used in the development of polymer-based materials and as a component in electronic sensors due to its unique chemical properties.

When handling 4-Chloro-7-fluoro-3-iodo-6-methoxyquinoline, it is crucial to use appropriate Personal Protective Equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a fume hood due to its volatility and potential health hazards. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. It is also advisable to refer to the Safety Data Sheet (SDS) for detailed safety information.